Course summary

Centre for Clinical Brain Sciences The Centre for Clinical Brain Sciences (CCBS) combines laboratory and clinical research to study the causes, consequences and treatment of major brain disorders. The Centre comprises 58 Principal Investigators, including 19 Chairs. 70% of our Principal Investigators are NHS clinicians. CCBS has approximately 55 postgraduate students across its two programmes: Clinical Brain Sciences and Psychiatry. It is particularly strong in PhD training for clinicians. The Centre is located at Edinburgh BioQuarter, next to the Royal Infirmary of Edinburgh. However, it also has bases in three other Edinburgh hospital sites. CCBS subscribes to Edinburgh Medical School’s “One Health” vision. Laboratory scientists, clinical academics and informaticians work alongside one another. This encourages the free-flowing exchange of ideas, an efficient use of clinical data and joint academic/health service delivery. CCBS is part of Edinburgh Neuroscience, an umbrella organisation that facilitates interaction among researchers working at all levels of neuroscience. Research excellence In the Research Excellence Framework (2014), Edinburgh was ranked 3rd out of 82 submissions in Neuroscience and the research environment was given the maximum possible score of 100% and classified as ‘world-leading’. Research community We are extremely proud of our internationally renowned research community. The Centre has attracted £42 million in grant funding over the last three years. Our 400+ members collaborate widely and lead international clinical trials. Our research generates significant and measurable impact on patient health and wellbeing, NHS policy and public awareness. The National Creutzfeldt-Jakob Disease (CJD) Research and Surveillance Unit is a World Health Organisation Reference Centre for Human Prion Disease. Two of our Professors are Chairs of the UK Dementia Research Institute at the University of Edinburgh. Research strengths Our major research strengths are:

• cerebrovascular disease including stroke and small vessel diseases

• neurodegenerative diseases: multiple sclerosis, motor neurone disease, dementias

• neuroimaging

• psychiatry, including schizophrenia, bipolar disorder and depression; autism, neurodiversity and learning disability

• Prion diseases

• synaptic biology & disease

• epilepsy

• neonatal development and the effect of premature birth

• neuro-oncology / Translational Neurosurgery

• functional disorders

• Anne Rowling Regenerative Neurology Clinic

• Edinburgh Dementia Prevention

• Euan MacDonald Centre for Motor Neurone Disease Research

• MS Society Edinburgh Centre for MS Research

• Muir Maxwell Epilepsy Centre

• Patrick Wild Centre for Research into Autism; Fragile X Syndrome and Intellectual Disabilities

• Salvesen Mindroom Research Centre for Learning Difficulties

• Theirworld Edinburgh Birth Cohort

• Row Fogo Centre for Research into Ageing and the Brain