Course summary

The MPhil is offered by the Department of Chemistry as a full-time period of research and introduces students to research skills and specialist knowledge. Students are integrated into the research culture of the Department by joining a research group, supervised by one of our academic staff, in one of the following areas of chemistry: Biological Chemistry Life is the chemistry that goes on inside every one of us. We seek to understand this chemistry, both the physical processes occurring at the molecular level and the chemical reactions, and we also seek to control the chemistry as a way to treat diseases. Biological Chemistry at Cambridge comprises several research groups with additional contributions from many more. The major themes are biological polymers, proteins and nucleic acids – how they interact with each other and with small molecules. How do proteins fold to a defined structure and why do they sometimes not fold properly but aggregate causing neurodegenerative diseases? How do proteins catalyse the reactions that they do and can we make small molecules that inhibit these processes? What structures can nucleic acids adopt? How can we detect and what is the role of modifications of individual nucleotides? How can we target medicinally active compounds to where they are needed in the body? By addressing these questions, we seek to improve human health and the treatment of diseases. Materials Chemistry The technological devices that we depend on, from aeroplanes to mobile phones, rely upon ever-increasing structural complexity for their function. Designing complex materials for these devices through the art of chemical synthesis brings challenges and opportunities. Members of the Materials Research Interest Group invent new materials to explore and develop fundamental concepts in view of potential applications. Our studies thus include surfaces, interfaces, polymers, nanoparticles and nanoporous materials, self assembly, and biomaterials. Physical and Atmospheric Chemistry Physical Chemistry at Cambridge has two broad but overlapping aims. One is to understand the properties of molecular systems in terms of physical principles. This work underpins many developing technological applications that affect us all, such as nanotechnology, sensors and molecular medicine. The other is atmospheric chemistry where the interactions between chemical composition, climate and health are studied using a range of computer modelling and experiment-based approaches. Together these two areas form a richly interdisciplinary subject spanning the full range of scientific methodologies: experimental, theoretical and computational. It is the research area with something for everyone. Synthetic Chemistry Synthetic research at the University of Cambridge is focussed on the development of innovative new methods to make and use molecules of function. Ranging from the innovative catalytic strategies to make small molecules, to supramolecular assemblies or the total synthesis of biologically important compounds, our research is diverse, pioneering and internationally leading. The dynamic environment created by the research groups working at the cutting edge of the field makes postgraduate research at Cambridge the best place for outstanding and motivated students. Theoretical Chemistry Research in Theoretical Chemistry covers a wide range of length and timescales, including active development of new theoretical and computational tools. The applications include high-resolution spectroscopy, atomic and molecular clusters, biophysics, surface science, and condensed matter, complementing experimental research in the Department. We develop new tools for quantum and classical simulations, informatics, and investigate molecules using descriptions that range from atomic detail to coarse-grained models of mesoscopic matter.