Course summary

The MPhil in Biological Sciences provides students with an opportunity to undertake a period of study and research in Biomolecular Science, one of the Faculty’s key research pathways. Biomolecular science is the study of biological processes at the molecular level, whether within a cell, a tissue, a whole organism or an ecosystem. As such its concepts and experimental approaches are absolutely central to the whole range of present-day life sciences. Biomolecular science is a rapidly evolving field: in the technologies it exploits to understand life at the macromolecular level and in its conceptual advances that drive basic research and support biotechnology applications. By combining traditional areas of science to unravel how molecular machines execute biological processes, biomolecular science transcends boundaries between the single disciplines of biology, chemistry, physics, and computer science. This MPhil aims to convey a comprehensive understanding of biological processes at the molecular level. We will discuss the major biological macromolecule families, including, DNA, RNA, proteins and lipids. We will explore the properties of biological membranes, biomolecular recognition, signalling and therapeutics. The understanding and application of advanced technologies are crucial to the advancement of biomolecular science and these will be explored in depth. Although we will not focus on specific diseases, the workshops and discussions will include relevant pathophysiological contexts, as understanding the molecular basis of disease will be imperative to developing innovations, from target-based therapeutics to agricultural applications. The course will draw upon the breadth and international strengths in biomolecular science within the University of Cambridge and associated research institutes; notably the Departments of Biochemistry, Genetics, Pathology, Pharmacology, Physiology Development and Neuroscience, Plant Sciences, Zoology, the Gurdon Institute, the MRC Toxicology Unit, the MRC Laboratory of Molecular Biology, the Sainsbury Laboratory and the Wellcome-MRC Stem Cell Institute. Completing this MPhil will be a springboard for entry into a wide range of careers, including advanced research in industry or academic settings. The MPhil is offered by the Faculty of Biology as a full-time period of study and research and introduces students to research skills and specialist knowledge in Biomolecular Science. The MPhil course adopts interactive and discussion-based teaching, much of which is seminar-style where student participation and discussion are strongly encouraged. This is complemented with extensive lab-based training during a research project (up to 32 weeks + 6 weeks writing up time) with students integrated into one of the many participating research groups (selected after starting the MPhil, having been introduced to projects and groups).